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Filtered Search Results
ABclonal Technology CDC123 Rabbit pAb
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Predicted to be involved in eukaryotic translation initiation factor 2 complex assembly and positive regulation of translational initiation. Located in cytoplasm.
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ABclonal Technology G3BP1 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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ABclonal Technology NOP16 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a protein that is localized to the nucleolus. Expression of this gene is induced by estrogens and Myc protein and is a marker of poor patient survival in breast cancer. Alternative splicing results in multiple transcript variants.
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Sino Biological Recombinant Human NCAM-1/CD56 Protein (Site-Specific PE Conjugation, His Tag) 100 Tests
A DNA sequence encoding the human NCAM1 (NP_001070150.1) (Met 1-Pro 603) was expressed with a C-terminal polyhistidine tag. The protein is site-specifically conjugated with PE (Excitation= 495 - 566 nm, Emission Max.= 575 nm).
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Sino Biological Recombinant Human IL-31RA Protein (His & AVI Tag), Avi-tag Biotinylated, HPLC-verified 20
A DNA sequence encoding the Huamn IL-31RA (EAW54932.1) (Met1-Thr516) was expressed with a C-terminal polyhistidine tag followed by an AVI tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
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Biotium Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker)(CPA1/2713), Biotin conjugate, 0.1mg/mL
Carboxypeptidase A1 (CPA1) is a secreted zinc metalloprotease that is highly expressed in pancreatic tissue. It catalyzes the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker) (PRF1/2468), CF488A conjugate, 0.1mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of
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ABclonal Technology MSP/MST1 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.
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Medchemexpress LLC Recombinant human cellular retinoic acid-binding protein 2 (CRABP2), His-tagged | >95.0% | 5 UG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Recombinant human cellular retinoic acid-binding protein 2 (CRABP2), His-tagged, supplied lyophilized for research applications involving retinoic acid binding and signaling. Expressed in E. coli, the protein has an approximate molecular weight of 16 kDa and is provided as a 5 μg vial in a Tris-NaCl formulation with low endotoxin.
- High purity greater than 95% as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Lyophilized format for long-term storage and convenient shipping.
- Recommended storage at -20°C; reconstituted stability at 4°C for 1 week.
- His tag facilitates affinity purification and detection.
- Formulated in 50 mM Tris-HCl, 300 mM NaCl, pH 8.0.
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Biotium Granzyme B (NK/T-Cell Lymphoma Marker)(GZMB/3055), CF488A conjugate, 0.1mg/mL
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommende
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Sino Biological Phospho-PDK1 (Ser241) Antibody, Rabbit MAb 100 µL
This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around Ser241 of Human PDK1.
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Biotium MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/2806), CF568 conjugate, 0.1mg/mL
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes of
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Sino Biological Recombinant Human RIOK2 Protein (Full length, GST Tag), Active 10 µg
Recombinant full-length human RIOK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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Biolegend TotalSeqTM-D0819 anti-human CD
TotalSeq™-D0819 anti-human CD126 (IL-6Rα) [UV4]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: PG; Size: 10 μg
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Bioss KD-Validated NDUFS3 Rabbit Rec
NADH Primary Antibody Unconjugated Public Immunogen Range 200-264/264 Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
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